Join us for a Science on Google+ HOA as we speak to Akinola Emmanuel and Dr shilpa keerthivasan about their recently…

Join us for a Science on Google+ HOA as we speak to Akinola Emmanuel and Dr shilpa keerthivasan about their recently published research on cancer signalling (http://stm.sciencemag.org/content/6/225/225ra28). We will discuss the basics of cancer signalling, explain the link between inflammation and cancer, and how their research identifies a novel role for immune cells in the development of colon cancer. This Pub Talks HOA will be part of a series in which we explain published research in a jargon-free manner that is understandable to the public.

This HOA will be hosted by Dr Buddhini Samarasinghe and you can tune in on Sunday March 23rd at 2 PM CDT/ 12PM PDT/ 7 PM GMT. The hangout will be available for viewing on our YouTube channel (https://www.youtube.com/ScienceHangouts) after the event.

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20 Comments


  1. Letha McGarity   We’ve used the Apc mouse model, but we’ve modified it to be specific either to T cells or epithelial cells so we can understand if the activation of Beta Catenin must be done in T cells or if it can be activated in epithelial cells in order for colitis to develop.

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  2. Chad Haney I think the induction of apoptosis has the potential to be very beneficial because apoptosis has been shown to lead to the production of molecules that are important for regulatory T cell development. How would you make it specific though?

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  3. Chad Haney very true, and that’s why the follow up is important. shilpa keerthivasan ‘s next step is looking into human regulatory T cells and understanding what genes are essentially malfunctioning. We’re trying to be specific by avoiding Beta Catenin and going after what it screws up in a particular cell.

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